Knowledge Coupling: Support for Psychiatric Decision-Making

Willie Kai Yee, M.D.
Psychiatric Applications Developer
PKC Corporation, Burlington, VT
To be published as a Chapter in Mental Health Computing, Edited by Marvin J.Miller,M.D., Kenric Hammond, M.D., Matthew Hile, Ph.D., Springer-Verlag , 1995
Draft only: Not for publication or citation
December 1994
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ABSTRACT

Problem Knowledge Couplers, computer programs created to aid health care professionals in making better clinical decisions, address, in their philosophy and implementation, limitations inherent in the process of medical decision-making. Decisions made using clinical judgment alone carry substantial risk of error, contributing to the cost of health care. This issue as well as other measures to actually improve the quality of health care by improving the well-being of the population and the appropriateness of care that is actually administered are being ignored. Problem Knowledge Couplers address the issues of decision-making, including prevention, patient involvement, and the utilization of support providers. Problems specific to the practice of psychiatry and mental health are addressed in Couplers created for psychiatric problems.


INTRODUCTION: PSYCHIATRIC DECISION- MAKING

The human mind has a limited capacity for retaining and processing knowledge. The simple facts that memory is imperfect, and that some problems are too complex to be solved by an individual brain seem obvious, but their implications for psychiatric practice are largely ignored. Recognizing and addressing these facts as they affect the process of medical decision-making is critical if health care is to be delivered more effectively.

Decision-making as discussed here refers to the clinical process of making diagnoses and selecting treatments based on that diagnosis. Psychiatric decision-making is subject to the same constraints as medical decision-making in general, and in addition must deal with 1) difficulties inherent in the state of psychiatric knowledge, as reflected in the literature, 2) the subjective, cultural, and individual nature of psychosocial problems, 3) ideological conflicts within the field, and 4) the context of psychiatric treatment and evaluation, which may involve the exploration of personally private and sensitive matters.
 
 

KNOWLEDGE LOSSES IN THE DECISION MAKING PROCESS

Medical-psychiatric decision making is a heterogeneous process. It may involve a spectrum of strategies ranging from the "hunch" of the clinician, to variably grounded and integrated clinical experience, to logical deduction based on a thorough review of the best available scientific data. Most clinicians will employ a variety of methods depending on the clinical situation and the information that is available to them.

There are severe limitations in this process. First, the decision process may involve multiple variables. The limitations of the human mind in this regard are well documented. Studies have shown that in a variety of areas, clinical judgment, the evaluation of multiple variables by the unaided human mind, is inferior to actuarial decision making, where evidence is combined and evaluated according to known rules and established statistical methods (Dawes, et.al., 1989).

Secondly, the recall of data is subject to numerous errors as applied to clinical situations. Fig.1 is a model for information accuracy as applied to the clinical decision. It begins with the data obtained in a study. The data is filtered as it is put into publication, and some of what may have been learned as clinically useful may not be included in the publication for various reasons. As the information is applied to the clinical situation, its relevance may be in question: the population in the study may not reflect the characteristics of the patient. For example, patients selected for an antidepressant medication trial may exclude those with a concurrent personality disorder. In clinical practice, however, depression and personality disorder frequently present together. Thus what was learned from the drug trial may not be applicable to the individual patient.

Further knowledge loss occurs as the information is reproduced in publications or presentations. The summarization procedure will inevitably leave out some material from the original publication. In some cases, what is selected will be that which is relevant to the clinical case. In others, what is left out may be deemed to be irrelevant to the purposes of a review or presentation, but may turn out to be essential to a particular patient.

Fig 1

Overall losses in knowledge occur because access to the information varies: information in papers or books that the practitioner has not read is not available to the decision-making progress (Huth, 1989). In this case, the information simply does not exist. If the practitioner has read or heard the material, errors of comprehension may enter: the material or its significance may be misunderstood (Evidence-Based Medicine Working Group, 1991). Finally, in the actual clinical situation, recall of the material is entirely dependent on the memory of the clinician. This is inconsistent at best, and may be decreased due to overwork, stressed, or preoccupation.

Once information is imparted to a patient, as in a recommendation or a prescription, additional knowledge losses occur (Fig. 2). The patient may not be presented with all the information that is relevant to the situation, may not hear or understand all that is presented, may not remember what was understood, and may not be motivated to follow what is remembered.

When viewed in toto, even small knowledge losses at each step add up to a potentially frightening degree of misinformation at the time that a treatment is administered.

Fig 2

SOLUTIONS: PHILOSOPHY AND TECHNOLOGY

The means to address these matters discussed above already exist. They involve the use of a new philosophy and appropriate technology brought to the process of clinical decision making.
 
 
Knowledge Couplers: Technology to aid clinical decision making
Problem Knowledge Couplers are computer programs developed specifically to aid clinicians in the process of making accurate clinical diagnostic and treatment decisions. Each Coupler covers a clinical problem as presented by the patient, either a symptom to be diagnosed or managed, or a known condition which requires management.

The Coupler begins with a series of questions that are answered by the clinician, or when practicable, by the patient. A click of a button creates, without further effort such as writing or dictation, a record of the findings for that patient. The list of findings is used by the program to vote for various diagnostic and management options. Both the findings and the options are present with appropriate comments which may be printed out and presented to the patient.
 
 

Principles of Rational Decision-making in Health Care

The elements of a required philosophy have been described by Lawrence L. Weed, M.D. (Weed, 1991):
 
  Each of these has relevance to mental health care, and raise issues particular to psychiatry.
 
 
A. Provide the best information tools available.
Few tools have been generally available to aid psychiatric decision making, although these have been under development at various institutions. These tools vary widely in their scope, reflecting their origins. Some have developed out of academic institutions use search and retrieval or artificial intelligence strategies. Others have developed from diagnostic classifications, especially the DSM, and from structured diagnostic interviews. The PKC system was developed for use in medical settings after an examination of the decision-making process itself, and a determination of what types of information access would be most clinically useful. Using the principles and tools of the PKC system, it has been possible to develop programs that address common psychiatric problems such as depression, anxiety, and psychosis.
 
 
B. Maximize the contribution of every provider.
Present day medicine has developed multiple roles, in addition to physicians (primary and specialty), for the provision of health care in specialty/technical areas (e.g., radiology technicians or ICU nurses) and in primary care (nurse practitioners and physician assistants). A shared knowledge base and a shared set of standards, terminology and conventions reflected in the medical record are essential to consistent and rational administration of health care by multiple providers, whether organized as a team or not.

 "Support providers" are used widely, especially in hospital and community psychiatry, and include psychologists, social workers, occupational and recreational therapists, psychiatric nurses, community mental health workers, and others. Although they may use a common medical record, and may participate in regular interdisciplinary treatment planning meetings, disparities in treatment philosophies, ideologies, and the arena of contact with the patients may lead to varying and conflicting views of the patient and his or her problems.

 Problem Knowledge Couplers address these conflicts by providing a common framework for evaluating a patient, and providing a problem list shared by all providers. Couplers are able to integrate knowledge from multiple disciplines, so that all providers have relevant information from other disciplines as diagnostic and treatment decisions are made. A means of including input from all providers (an 800 phone number) allows the Coupler to become a mechanism for the cumulative and cooperative acquisition of knowledge across professional boundaries.

C. Couple knowledge to action on the patient's behalf.
All clinical decision making involves the retrieval of information from a base of knowledge, and selecting and combining that information which is relevant to the clinical problem. Computer tools can extract that knowledge which is relevant to the situation. Proper program design means that the clinician will not have to depend on memory or wade through a textbook, library, or computer database to have access to the most appropriate material.

In addition to remembering a base of technical knowledge, applying it to a clinical problem involves the correlation of multiple variables of the clinical situation (history findings, symptoms, physical examination, mental status, and laboratory results) with the variables presented in the literature. A given problem may involve dozens of diagnostic possibilities each with several findings, many of which overlap. The number of combinations exceeds the capacity of the human mind to carry out a complete correlation. Mental strategies used in such situations inevitably involve simplifications, abstractions, and other methods that omit information, and carry the risk of introducing error into the decision making process.

 Accurately correlating multiple variables is something that computers can do well. Although much research and discussion have gone into discussing the representations of knowledge (algorithms) that are best used, it has been shown that even the simplest models (linear models or simple but accurate lists) can aid accurate clinical decision making (Dawes and Corrigan, 1974).

 As psychiatric knowledge expands and is put on a more scientific basis, the application of that knowledge remains in a centuries-old mode. The number of effective interventions that have been demonstrated continues to increase. For example, the number of antidepressants presently available on the market is close to twenty, with a half dozen classes of augmenting or alternative agents, and many medications that may be used for comorbid conditions. Although all are effective against depression, the literature lists a number of demonstrated indications and contraindications for each agent and class of agent. Published guidelines may attempt to rationalize the selection of medication, but these leave out details that may be relevant to an individual patient, and again rely on the memory and processing capability of the clinician to implement them.

Knowledge Couplers written for psychiatric problems are able to create the relevant links between the ever-expanding psychiatric literature and the unique presentation of the individual patient. Beginning by asking those questions which should be asked for every problem, a Coupler is able to produce the links to all relevant knowledge from the literature, including the rare illness, the disorder that is the province of another medical specialty, and the multiple causes that may be present in a complex case.

D. Put the patient at the center of the healthcare process.
Discussions of healthcare reform largely proceed on the assumptions that patients are passive recipients of health services, and that the provider is at the center of the process. True reform must recognize the patient is the final arbiter of health care actions, and must recognize patients as active participants. When patients themselves are seen as the primary providers of health care, and information access is restructured to facilitate that process, compliance increases, prevention is emphasized, and healthcare costs are brought down in numerous ways (Ferguson, 1987). Similarly, the recognition of families as a healthcare delivery system has a demonstrated impact on the course of psychiatric illness, as shown by the abundant literature on the psychoeducational family treatment of schizophrenia.

 Psychiatric implementation of this involves an educational component that helps to relieve stigma, utilize resources, such as self-help groups, that lie outside the province of formal psychiatric care. Respect is maintained for the patient's ability to determine the combination of symptom severity, disability, side effects, risks, benefits, and costs that he or she wishes to live with.

Knowledge Couplers provide a key link in transforming the center of health care decision making. Their use in the earliest phases of evaluation, and the provision of information that has been selected to be specifically applicable to the problem at hand insures that the importance of the consumer is recognized. As the patient reviews the Coupler output with the provider, a collaborative, rather than passive and dependent relationship is established.
 
 

E. Provide real means for the continuous improvement of quality.
The vast amount of information available is both a blessing and a curse. From a scientific and clinical point of view, this is a wonderful time to be in the field of psychiatry. New medications, greater understanding of brain function, and the establishment of a firm research foundation for various psychosocial treatments make psychiatry an exciting and challenging field. The difficulty here, as in all rapidly advancing fields, is that the explosive growth of knowledge makes it impossible to keep abreast of all significant information, especially while engaged in a busy practice. Even if one is able to keep up to date, the knowledge losses described above render the application of knowledge to the clinical situation a haphazard process.

Computer systems have the ability to track large amounts of information, and to provide for regular updating of that information. Implementation of the PKC system includes regular updating of information as it is reviewed by in the literature by Coupler authors and as suggested by users of the PKC system.
 
 

F. Remove the risks associated with variation among providers.
Psychiatry is making progress in establishing a consistent language for diagnosis (the DSM), and standards for the treatment of psychiatric disorders (practice guidelines). The actual implementation of these at the level of the practitioner still remains a haphazard process. The training, philosophies, and literature bases of various disciplines result in additional variation in case evaluation and management between providers of different disciplines. Knowledge Couplers, based on the problem-oriented approach, however, insure that relevant knowledge from all disciplines is available to all providers.

Consistent input is applied to every case, regardless of the practitioner's specialty, discipline, training, orientation, or practice setting. While diagnostic classifications, clinical guidelines, and computer- based knowledge systems cannot reduce the variation associated with individual patients, consistent input can be used to ensure that all providers are working from the same database of information about the patient, and from the same base of knowledge derived from the literature.

G. Deliver precisely and ethically the necessary and sufficient care each patient requires.
Health care reform has involved a discussion of the financing of health care. Insurance schemes, mandatory coverage, caps on services, and public financing (i.e., taxes) are the language of such reform. Managed care attempts to control costs by limiting care on the basis of utilization statistics of populations of patients. The characteristics of individual cases that may justify care may be overlooked in the routine processing of requests for authorization or the often strained negotiation between authorizers and providers of care.

Limiting costs in this context involves limiting services in some way, either directly through caps on services, or indirectly by limiting fees or taxing benefits. Little discussion is given to the role of preventive care, other than in a few areas such as prenatal care, where a clear cost benefit advantage has been shown. Although there is discussion of the role of guidelines to limit the inappropriate use of expensive technology, there is no discussion about how guidelines or any other relevant medical information is actually used in the patient-physician interaction (Weed and Weed, 1994). Indeed, the topic of the patient-physician interaction is seen as a taboo subject, and the role of information technologies in this interaction is a matter left to a few specialists.

 Computer software can be used to select treatment that is appropriate by matching the characteristics of the individual patient to those that have been shown to identify safe and effective treatments. Superficially, this may appear to be the same process as that utilized by managed care. The difference is that the coupling of information takes place as part of the process of clinical diagnosis and treatment, rather than an additional procedure that is imposed upon it. For example, cognitive therapy may be a recommended treatment for some depressions. If some other form of therapy were being practiced by the therapist, the recommendation for cognitive therapy by a managed care representative may be seen as an invasion into the therapeutic process. If this recommendation appeared at the time that the treatment was planned, it could be reviewed as an option by provider and patient together, taking into account the provider's skills and patient preference.

Utilizing continuously updated software provides a way of rationally integrating newer treatments into clinical practice. Techniques that the clinician may not have learned during professional training can be brought to the clinician's attention at the time when it is most appropriate to consider them for application, rather than at a distant time that may be convenient to the schedule of the clinician or the presenters of the information. It also allows newer treatments to be evaluated appropriately in the context of information about established treatments, with both risks and benefits available. The over-prescription of newer medications because of pharmaceutical company marketing efforts, and their under-utilization, due to reluctance to employ unfamiliar treatments and lack of adequate information, can be overcome by software that can provide the precise amount of information that the situation requires.

HEALTH CARE REFORM

By ignoring issues that would improve health, make better clinical decisions, and better utilize existing services and technologies, the focus on economics will paradoxically result in poorer overall health of the people and greater cost of health care. Only by redirecting the goal of reform from how to pay for health insurance to how to improve the health of the citizenry can true cost control be achieved.
 
 

KNOWLEDGE COUPLING IN CLINICAL PRACTICE

Problem Knowledge Couplers have been used for several years in a variety of psychiatric settings. The experience of users indicates fewer problems with acceptance than anticipated, and unexpected benefits.
Patient acceptance of computer usage
Patients generally accept the use of the computer as part of a psychiatric evaluation. Except for paranoid patients, discussed below, I have never had a patient object to the use of the computer during an evaluation. Most patients react to the computer positively. They feel they are being evaluated with state-of- the-art methods, and that the physician is being thorough. Some patients have stated that the computer evaluation is evidence of personal treatment. This is particularly true if they are given a printout for their own use either during the session or after the session.

 R. Vance Fitzgerald, M.D., of the Medical College of Ohio at Toledo, reports that men seem to be more accepting of the use of computers than women. He writes:

 "For some patients I deliberately elect NOT to use the Coupler in their presence. I am not entirely clear about how I arrive at this decision. I think it has something to do with the patient's sensitivity and compelling need for an interpersonal connection and, perhaps, to my sense that a patient has a bias against things mechanical. I may be particularly sensitive to this aspect of possible patient reaction because of knowing my wife's feelings and those of other women I talk with about computers. I don't mean this in a sexist way. Most of the patients I chose not to use a Coupler with are women. Many men and many women are different in regard to feelings about this procedure.

 "Men, generally, seem more impressed. To them it's more logical and indicates that the expert is one up compared to other experts who do not use modern technology (Fitzgerald, 1992)."
 
 

Dealing with the paranoid patient
Paranoid patients may object to the use of the computer. I have handled this simply by asking the patient to sit by my side where he/she can see the screen while I run the program. Paranoid patients are usually quite curious, and will take the opportunity to see what is happening. Once they have accepted this offer, they have now become allies with me against a new "adversary" - the computer. After several minutes using the PKC system, I have found most paranoid patients lose interest, probably because screen after screen of text lacks the appeal of video games and other computer graphic displays that they may have been exposed to. At this point, however, the mistrust of the computer is no longer an issue.

 Paranoid patients may object to or falsely answer some questions in the Coupler "Psychotic-like Behavior, Thinking, and Speech," the one that is most likely to be used in their cases. This can be overcome be running a Coupler that is more neutral for them, such as Anxiety or Depression, first. The patient may then lose interest in specific questions before the Coupler for psychosis is run.
 
 

Psychiatrist resistance
Resistance, usually passive, to the use of the computer in clinical settings is more likely to come from the psychiatrist than the patient. Patients may pick up the psychiatrist's discomfort with the situation, and may then express the discomfort as their own.
 
 

Use in Clinical Practice

One user said of the PKC System "It's like having a friendly consultant at your side." For practitioners in solo practice, or working in isolated areas, the PKC System can be a valuable resource in maintaining and augmenting their own clinical skills.

 To serve its function, the PKC system should be used on a regular basis. I routinely do the appropriate Couplers on all evaluations. Occasionally, on what appears to be a clear cut case, I will omit doing the Coupler. Within a few weeks, I usually regret the decision, and do the Coupler at that point.
 
 

Integration of Couplers into psychiatric evaluation
There are several approaches to utilizing Couplers in the actual clinical situation of evaluating and treating patients. The three that follow discuss the various points in the evaluation at which the Couplers may be run, along with the pros and cons of each approach.
 
 
After the clinical evaluation
The Coupler appropriate to the patient's problems may be run after completing the clinical evaluation and allowing the patient to leave the office. This has several advantages. If the clinician is just becoming familiar with the PKC System, this will allow time to study the all aspects of the Coupler, and to become more adept at handing the mechanics of navigating the Coupler system.

One disadvantage of this method is that the user will inevitably find a few questions that were not asked during the interview. Since the use of a Coupler requires that the user answer all questions, the accuracy of the data generated will be compromised. One of the reasons that Couplers were developed was to be certain that all pertinent questions were asked, and this method is likely to defeat that purpose.

 Another difficulty is that the results of the Coupler are not available at the time decisions are made. For a diagnosis, this may just mean adding a chart entry, but if it affects treatment, the patient may be unavailable or confused by an alteration of treatment plan at this point.

 In short, running a Coupler after a clinical evaluation should be done only as a training exercise, or in those rare occasions in which the Coupler session for some reason cannot be completed in the patient's presence.
 
 

Toward the end of interview
The clinician may conduct the interview as he or she usually does, and run the Coupler just before presenting the assessment and treatment plan to the patient. The Coupler may be introduced by a comment such as "I would like to enter some information into the Computer to make sure I do not forget anything." As the clinician selects the appropriate responses in the Coupler, she may ask the patient to answer any questions that were not asked during the earlier part of the interview. After the coupling the Findings, the results may then be discussed with the patient.

 This allows the clinician to evaluate the patient with little disruption of his or her usual style, and still allows access to the results of Coupling as treatment decisions are made. This also allows the clinician who may not entirely trust or understand the coupling process to form her own clinical opinion, against which the Coupler-generated options may be compared.

 Patients may sometimes feel that the clinician is involved in some secretive process from which he or she is being excluded. This may be handled by inviting the patient to observe the computer screen as the data is entered. This procedure also allows the patient to confirm the accuracy of responses as they are selected.
 
 

During the evaluation of present illness
The Coupler may be run as soon as the main problem has been determined, near the beginning of the clinical interview. This allows the integration of the information gathering process for the Coupler into the clinical interview. The running of the Coupler becomes part of obtaining the history of the present illness and stresses its importance to both patient and practitioner. The clinician asks Questions relevant to the patient's complaint at the time the patient presents the problem, and establishes the use of the computer as a natural part of the evaluation process.

 Running the Coupler early in the interview may mean that the evaluation process may be limited to the evaluation of the presenting problem. In an emergency, this may be acceptable, and may allow for prompt evaluation and initiation of treatment. There is, however, a risk that the evaluation may end here, and that other essential tasks such as obtaining a complete problem list or a thorough past history may be ignored.
 
 

Before the interview
Another procedure that may be employed in clinic settings is to have a skilled interviewer, e.g., a psychiatric social worker, nurse, or other trained interviewer, run the Coupler before the evaluation. This makes the Coupler results available at the time of the evaluation. None of the physician's time is used to enter data into the computer, and the interview may proceed as usual.

 As in the situation above, where the psychiatrist runs the Coupler, the clinician must decide when to run the Coupler. The major difference is that the discussion of Coupler results may not take place immediately after the Coupler is run because some of the content of the Coupler may be considered beyond the knowledge level of the interviewer. In a mental health setting, medical issues are more likely to be beyond the scope of a mental health worker, and in medical settings, psychotherapeutic issues may be unfamiliar to medical personnel.

 Although this may be a more efficient use of the psychiatrist's time, this procedure risks minimizing the importance of the coupling process, and the Coupler results could even conceivably be ignored, just as critical laboratory reports may be overlooked.
 
 

Time required
After becoming familiar with the structure of a Coupler, it takes about 10 minutes to ask all the questions contained in a Coupler. Most of these are questions that should be asked in the evaluation of the problem anyway, and answers are keyed in by pressing single number keys (i.e., no typing is involved). The actual amount of time that it adds to the evaluation is minimal.

 If the patient presents with multiple complaints, more than one Coupler may need to be run. I have found that two Couplers can be run without interfering with the evaluation process. If an evaluation requires more than two Couplers, it is best to schedule them over more than one session. Again, there is probably no additional increase in time involved, since these are cases that require a longer evaluation anyway.

 The Personality Disorder Coupler is the only psychiatric Coupler that may take more than 10 minutes to run, because it contains questions for each of the individual criteria of all the DSM-III-R Personality Disorders. Because of this, a self- assessing questionnaire, the PsyComNet Self-Assessing Personality Disorders Inventory by Ivan Goldberg, M.D., has been adapted for use with the PKC System. The patient completes the questionnaire, and a clerical person can enter the data directly into the Personality Disorder Coupler using the "Add to the List of Findings" command from the "Other Functions" screen. This process takes about 10 minutes of clerical time, not counting time to print out the report. The results of the questionnaire, as with all self-assessing instruments in personality disorders, must be interpreted with caution.
 
 

CONCLUSION

Unaided psychiatric decision making depends on processes that have limitations that have been defined by cognitive science, and which are becoming inadequate to handle the volume and complexity of psychiatric knowledge. Tools, such as Problem Knowledge Couplers directly address these limitations. Clinical experience has shown that the use of these knowledge tools in psychiatric practice is beneficial and acceptable to both practitioner and patient.


REFERENCES

Dawes, R.M., and Corrigan (1974) Linear models in decision making. Psychological Bulletin, 81, 95- 106.

 Dawes, R. M., Fust, D., and Meehl, P.E. (1989) Clinical versus actuarial judgment. Science, 243, 1668-1673.

 Ferguson, T. (1987) Health in the information age: sharing the uncertainty. Whole Earth Review, 57, 130-133.

 Fitzgerald, R.V. (1992) Personal communication.

 Huth, E.J. (1989) The underused medical literature. Annals of Internal Medicine, 110, 99-100.

Hyler, S. E., et.al., A Comparison of Clinical and Self- Report Diagnoses of DSM-III Personality Disorders in 552 Patients, Comprehensive Psychiatry, 30 (2), Mar-Apr 1989, pp. 170-178.

 Oxman A.D., Sackett, D.L., Guyatt, G.H. (1993) Users' guides to the medical literature: I. How to get started. Journal of the American Medical Association, 270, 2093-2095

 Weed, L. L., and Weed, L. (1994) Reengineering medicine. Federation Bulletin: J. Medical Licensure and Discipline, 81, 149-183.

Weed, L. L. (1991) Knowledge Coupling: New Premises and New Tools for Medical Care and Education, New York: Springer-Verlag.